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# Principal Statistical Programmer

- **Company:** IQVIA
- **Location:** Durham, NC, United States
- **Experience:** Expert
- **Salary:** $98,200.0 - $273,200.0
- **Contract:** Permanent contract
- **Skills:** Clinical Data Repository, Data Structures, R (Programming Language), Python (Programming Language), SAS (Software), Information Technology
- **Published:** June 29, 2026
- **Apply:** https://www.healthjobsnationwide.com/job/principal-statistical-programmer-14826736

## About the Role

* Education: Advanced degree in Statistics, Computer Science, Biostatistics, Life Sciences, or related field.

 * Experience: 10+ years in statistical programming within pharma/biotech; expertise across clinical trial Phases I-IV, regulatory submissions, CDISC, RWE, HEOR, HTA.

 * Technical Skills: Proficient in SAS & R; Python, Shiny preferred; solid understanding of clinical data standards.

 * Soft Skills: Strong leadership, mentorship, presentation, and negotiation skills; problem-solving ability and judgment in regulatory/technical contexts.

## Description

Program Leadership: Lead statistical programming across multiple trials or programs; guide both internal and external teams.

 * Team & Line Management: Mentor junior staff; act as functional manager for associates; represent Statistical Programming at governance meetings.

 * Technical Expertise: Strong SAS, R, CDISC SDTM/ADaM/Define.xml, eCTD knowledge; familiarity with eCRF/data structures.

 * Deliverable Quality: Ensure QC, validation, audit readiness, and regulatory inspection readiness; deliver datasets and outputs for CSRs, safety reports, publications.

 * Cross-functional Collaboration: Partner with clinical, statistical, HEOR, and IT teams; coordinate with external vendors.

 * Innovation & Process Improvement: Lead process improvements, apply new analytics capabilities, HTA/HEOR solutions, advanced tools (R/Shiny, automation).


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