Lead Full Stack Software Engineer (C#/.NET) - Remote

We are seeking a Lead Full Stack Developer responsible for designing, building and operating end-to-end web applications and data driven solution. This is a hands-on technical leadership role, combining senior individual contributor responsibilities with mentoring and guiding other developers on modern practices. This role requires recent hands-on experience owning technical solutions and driving projects forward while maintaining Full Stack Development responsibilities. Responsibilities

• Oversees application development team's technical delivery across all projects while remaining a hands-on Full Stack Developer.

• Design and implement scalable, secure frontend and backend components, including APIs, services and UI workflows, following clean architecture and solid principles.

• Embed application security best practices into the software development lifecycle, including securing code, code scanning, dependency management, and remediation of vulnerability identified through AppSec tools.

• Collaborate with product owners, technical analysts, project managers, platform engineering and analytics teams to translate complex business needs into practical technical solutions.

• Own technical solutions end to end: architecture, implementation, testing, deployment, and support.

• Establish and champion coding standards, automated testing, and CI/CD pipelines to improve quality, reliability and release frequency. Mentor and guide other developers; enforce engineering best practices, code quality, and architectural integrity.

• Collaborate with Solutions Architect, DevOps, and Data teams to translate business needs into scalable technical designs.

• Design secure integrations with external clinical and operational systems.

• Troubleshoot complex system issues and lead root cause analysis.

• Drive continuous improvement in cloud performance, cost optimization, security posture, and CI/CD automation.

• Understand and continue to stay current with the AWS Cloud development environment and tools that the systems utilize.

• Manage time effectively and accurately estimate effort for tasks and meets agreed-upon deadlines.

• Adapt to frequently changing requirements, priorities, and schedules.

• Troubleshoot and resolve technical issues in a timely manner, performs root cause analyses, and drives permanent fixes and technical debt reduction.

• Contribute to architecture discussions and technology choices, balancing innovation with maintainability and regulatory constraints.

• Promote a culture of documentation, knowledge sharing and continuous learning within the application development team. Provide technical mentorship and oversight through design reviews, pairing programming and structured feedback., Who We Are: Celebrating 40+ years! Theradex Oncology is a full-service CRO specializing in oncology. The company manages global oncology trials and programs. The company was fo…

• 1 month ago

• 8 years of experience as a full stack developer

• 3 years of experience leading a development team focused on building On-prem and Cloud applications Core stack C#/ASP.NET, .NET, Angular, SQL, NO SQL, and AWS

• Proficient in Angular and experience in a recent project

• Strong experience redeveloping on-prem web applications to be optimized for the AWS Cloud

• Experience leading a Cloud software development project end to end: architecture, implementation, testing, deployment, and support

• Experience building AWS based web sites, applications and integrations

• AWS services such as CloudWatch, SES, S3, ECR, ECS, Lambda functions

• UI/UX experience using Blazor or Angular

• Relational and non-relational databases

• All aspects of GitHub, including GitHub Actions

• Experience with Docker containers

• Strong experience with the management of code through a CI/CD pipeline

Preferred Experience

• Experience configuring AWS environment using Terraform, Fargate, etc.

• Experience in a CRO/pharmaceutical environment with definitive knowledge of regulated clinical data applications

• Knowledge of GxP and 21 CFR Part 11 compliance

• Experience with migrating an entire on-prem data center to the AWS Cloud

** This position requires the indivdual be either a US citizen or Green Card holder. **

Colgate-Palmolive + Piscataway, NJ + $86,000-137,000 per year Established in 1806 as a small soap and candle business in New York City, Colgate-Palmolive is now a truly global company with products sold in over 200 countries and territories u…, © 2026 Careerjet All rights reserved