Sr. Engineer - DSP

We are seeking a Chemical Engineer to join our Downstream Processing (DSP) Development team, focused on bench-scale process development for biologics/bioproducts and the translation of those processes to pilot and commercial manufacturing. You will design and execute experiments at bench scale (e.g., mL-L), develop robust purification steps (chromatography, filtration, precipitation, etc.), and work cross-functionally to transfer your process to industrial scale.

This role is ideal for an engineer who enjoys hands-on lab work, rigorous data analysis, and solving scale-up challenges with the end goal of commercializing processes at industrial scale. Traveling to partner sites for troubleshooting and overseeing tech-transfer is likely., * Bench-scale process development and optimization.

• Design, execute, and analyze experiments using purification unit operations (e.g., depth filtration, centrifugation, TFF/UFDF, chromatography, precipitation, etc.).
• Build methods and strategies to define scalable operating ranges, identify critical process parameters, and improve yield, purity, and throughput for purification unit operations.
• Support tech transfer to internal or external manufacturing sites, including documentation, protocols, and general transfer of process knowledge.
• Translate bench-scale findings into continuous models to predict process flow rates, unit sizes, and overall process costs.
• Author and review development reports, batch records, protocols, and technical assessments to enable stage gates
• Maintain high standards for data integrity, traceability, and reproducibility; ensure experiments and documentation align with internal quality systems and regulatory expectations.
• Collaborate with Upstream, Analytical, Quality, Regulatory, and Business teams to ensure end-to-end process performance and timeline execution.
• Communicate results clearly in team meetings and technical reviews; present recommendations backed by data and risk-based reasoning.

Do you have experience in Technical writing within manufacturing?, Do you have a Bachelor's degree?, * B.S. or higher in Chemical Engineering, Biochemical Engineering, Bioengineering, or a related discipline.

• 5+ years (B.S.) or 0-2 years (M.S./Ph.D.) of relevant experience in small molecule purifications, bioprocessing, or process development (industry or strong graduate/lab experience).
• Hands-on experience with one or more of the following:

• Chromatography (resin screening, column packing, scale-down models)
• TFF/UFDF systems (membrane selection, flux optimization, shear sensitivity, fouling mitigation)
• Crystallization (solubility studies, process design, solid-liquid-separation methods)
• Continuous process modeling (using advanced software packages or manually)

• Proficiency in experimental design and data analysis (Python, R, Excel, etc.)
• Strong technical writing skills, * Experience with scale-up/tech transfer and/or supporting manufacturing campaigns.
• Knowledge of process characterization, risk assessment (FMEA), and concepts such as QbD.
• Availability to travel
• Experience developing cost-of-goods (COGs) awareness and capacity/throughput assessments.
• Comfort with lab safety practices, equipment maintenance, and methodical troubleshooting.

The anticipated base salary for this role is $125,000 - $155,000 per year. Final compensation will be determined based on experience, skills, and geographic location, and may include bonus eligibility and a full benefits package.