Lead Knowledge Graph Engineer
Role details
Job location
Tech stack
Job description
- Platform Assessment: Conduct comprehensive technical health checks on existing graph databases and cluster infrastructure.
- Ontology & Schema Review: Evaluate RDF/OWL and Labeled Property Graph (LPG) schemas for enterprise scalability.
- Standards Alignment: Map internal data frameworks to biomedical standards like MeSH, SNOMED, and UMLS.
- Performance Optimization: Eliminate data bottlenecks across real-time ingestion pipelines and complex query execution.
- Strategic Roadmap: Author comprehensive "Way Forward" reports detailing cloud migration and build-vs-buy decisions.
- AI & LLM Integration: Design infrastructure to connect knowledge graphs with Large Language Models using GraphRAG frameworks.
- Stakeholder Alignment: Translate technical graph concepts into clear business value for Research and Clinical teams.
Requirements
Graph Expertise: 10+ years of engineering experience with Graph Databases, Triple Stores, or Labeled Property Graphs. Technical Stack Preferences
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Graph Databases: Stardog, AnzoGraph, or Neo4j
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Query & Programming Languages: SPARQL, Cypher, Gremlin, Python, and Java
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AI Tools: Any Vibe Coding Tool (Claude Code OR GHCP) Pharma Domain Knowledge -
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Pharma Domain Knowledge: Proven track record handling biomedical data like gene-disease associations and chemistry structures.
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CMC Data Familiarity: Experience modeling Chemistry Manufacturing and Control data types, including product journeys and electronic data capture logs.
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Bio-Ontologies & Datasets: OBO Foundry, ChEMBL, Ensembl, and Monarch Initiative
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Advanced AI/GenAI: Hands-on experience designing and executing Graph RAGs, Context Graphs, Agents
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Semantic Web Standards: Deep understanding of W3C standards, Linked Data principles, and URI minting strategies.