Lead Knowledge Graph Engineer

Upbeat Ideas UK Ltd
Charing Cross, United Kingdom
10 days ago

Role details

Contract type
Permanent contract
Employment type
Full-time (> 32 hours)
Working hours
Regular working hours
Languages
English
Experience level
Senior

Job location

Charing Cross, United Kingdom

Tech stack

Java
Artificial Intelligence
Electronic Data Capture
Graph Database
Python
Linked Data
Neo4j
Performance Tuning
Semantic Web
SPARQL
Large Language Models

Job description

  • Platform Assessment: Conduct comprehensive technical health checks on existing graph databases and cluster infrastructure.
  • Ontology & Schema Review: Evaluate RDF/OWL and Labeled Property Graph (LPG) schemas for enterprise scalability.
  • Standards Alignment: Map internal data frameworks to biomedical standards like MeSH, SNOMED, and UMLS.
  • Performance Optimization: Eliminate data bottlenecks across real-time ingestion pipelines and complex query execution.
  • Strategic Roadmap: Author comprehensive "Way Forward" reports detailing cloud migration and build-vs-buy decisions.
  • AI & LLM Integration: Design infrastructure to connect knowledge graphs with Large Language Models using GraphRAG frameworks.
  • Stakeholder Alignment: Translate technical graph concepts into clear business value for Research and Clinical teams.

Requirements

Graph Expertise: 10+ years of engineering experience with Graph Databases, Triple Stores, or Labeled Property Graphs. Technical Stack Preferences

  • Graph Databases: Stardog, AnzoGraph, or Neo4j

  • Query & Programming Languages: SPARQL, Cypher, Gremlin, Python, and Java

  • AI Tools: Any Vibe Coding Tool (Claude Code OR GHCP) Pharma Domain Knowledge -

  • Pharma Domain Knowledge: Proven track record handling biomedical data like gene-disease associations and chemistry structures.

  • CMC Data Familiarity: Experience modeling Chemistry Manufacturing and Control data types, including product journeys and electronic data capture logs.

  • Bio-Ontologies & Datasets: OBO Foundry, ChEMBL, Ensembl, and Monarch Initiative

  • Advanced AI/GenAI: Hands-on experience designing and executing Graph RAGs, Context Graphs, Agents

  • Semantic Web Standards: Deep understanding of W3C standards, Linked Data principles, and URI minting strategies.

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