Software Developer - Bioinformatics (ETL & Object Oriented Programming)
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Job description
research group at Boehringer-Ingelheim’s US research facility in Ridgefield, CT. The successful candidate will contribute to drug discovery efforts through analysis of multiple disease-relevant data sets, as well as development of core informatics pipelines and data organization.
- Strong scientific understanding and experience in computer science or bioinformatics
- Work closely with internal genomics core groups and external CROs to enable data transfer/processing
workflows to enable FAIR data
- Leverage sample management, LIMS and other FAIR data resources to ensure efficient workflows
- Design, implement and/or deploy NGS data analysis workflows for data processing, visualization,
integration and mining to support novel therapeutic target identification and disease biomarker discovery o Data Analysis: Implement methods for omics data analysis, and interpretation of genomic data sets (e.g., bulk RNA-seq, scRNA-seq, ATAC-Seq) o Data Visualization: Fluency in contemporary data visualization methods like R Shiny , D3 o Data Integration: Analyzing diverse datasets (multi-omics) to find relevant drug discovery targets and downstream effects relevant to immune disease o Data Mining: Internal, collaborative, and public databases to assist in the characterization of Immune disease
- Select, and benchmark methods and tools, define and perform appropriate QC measures
- Apply and develop innovative analysis approaches when standard methods are not adequate
- Interpret and present analysis results to coworkers and collaborators
- Follow relevant scientific literature to ensure use of optimal methods and understand emerging practices
across the field
- Demonstrates the ability to interpret the outcome of experiments, propose appropriate follow-up, and may
propose new avenues of investigation
- Communicates own work effectively orally and in writing; contributes to writing protocols, procedures, and
technical reports
- Automate processing and results reporting and delivery
- Experience with at least one object oriented language
- Reports and treats data with a high level of integrity and ethics
- Complies with applicable regulations; Maintains proper records in accordance with SOPs and policies
- Experience working in genomics lab setting
Requirements
- PhD degree (or equivalent) from an accredited institution in a related scientific discipline OR Master’s
degree from an accredited institution with six-plus (6+) years of experience in a related scientific discipline OR Bachelor’s degree from an accredited institution with ten-plus (12+) years of experience in a STEM discipline.
- The successful candidate will have experience with more than one of the following; analyzing nextgeneration
sequencing (NGS), functional genomics, statistics for big data analysis, or multi-omics data integration
- Good knowledge of existing bioinformatics databases and file formats
- In-depth understanding of computational methods for NGS analysis and the usage of public data resources
required
- Strong hands-on skills in relevant programming languages (e.g., R, Python, Shiny, UNIX/Linux, UNIX bash
shell scripting, Nextflow), statistical software, cloud computing, visualization tools, and relevant R/Bioconductor packages
- Demonstrated ability to produce well-designed and documented code
- Familiarity with computational biology tools and experience working with computational biologists to solve
problems
- Must enjoy working in a multi-disciplinary and collaborative environment
- Ability to troubleshoot both individually and as part of a team
- Excellent oral and written skills with the ability to communicate in an open, transparent, timely and
consistent manner QUALIFICATION/LICENSURE Work Authorization : Green Card, US Citizen Preferred years of experience : 3 years Travel required : No travel required
Benefits & conditions
4.04.0 out of 5 stars United States $55.00 - $63.07 an hour
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