Drug Discovery Principal Information Security Engineer

As a Principal Information Security Engineer - Agentic AI, you will serve as a vital catalyst within a premier organization. The mission is to decouple systemic friction from analytical progress, allowing the firm’s leadership to maintain a singular focus on the acceleration of Molecular Dynamics Simulation and Computational Biochemistry.

You will be tasked with the sophisticated management of Threat Mitigation and AI Security Automation, transforming abstract organizational needs into formalized, actionable results. This role requires a high degree of technical literacy to effectively support a team leveraging proprietary architectures and sophisticated algorithms to revolutionize Drug Discovery and Atomic-Level Molecular Design.

Core Technical Objectives

• Orchestrate Systemic Workflows: Develop, formalize, and improve upon robust security processes and high-stakes technical workflows to ensure a continuous, secure operational flow.
• Secure Agentic AI Frameworks: Focus intensively on deploying security tools, evaluating potential threats, and architecting defenses specifically tailored to secure autonomous, agentic AI systems and workflows.
• Optimize Operational Frameworks: Implement and manage advanced automation paradigms to proactively detect, mitigate, and resolve common security issues and vulnerabilities.
• Engineer Multi-Project Solutions: Independently manage a diverse portfolio of security domains-ranging from operational DevSecOps and penetration testing to endpoint detection and response (EDR)-applying a proactive approach to solve emergent bottlenecks.
• Facilitate Elite Communication: Serve as a discreet and articulate interface between the security ecosystem and internal scientific stakeholders, translating complex vulnerability metrics into coherent, actionable risk frameworks.

• Architectural Philosophy: A mindset rooted in efficiency and resilience, with the ability to navigate a hybrid, high-pressure environment with autonomous precision.
• Resourceful Problem-Solving: Strong programming and scripting ability coupled with a proven track record of automation, demonstrating the ability to anticipate systemic bottlenecks before they impact the broader scientific workflow.
• Communication Precision: Exceptional interpersonal and communication skills characterized by clarity, discretion, and the ability to seamlessly interact with elite scientific and business minds.
• Cross-Functional Agility: An adaptive execution style capable of pivoting effortlessly between rigorous security operations (threat detection, vulnerability management) and cutting-edge technical inquiry within a high-performance ecosystem.

Academic & Research Pedigree

• Educational Foundation: An advanced degree is preferred, ideally within Computer Science, Cybersecurity, a STEM discipline, or a quantitative field directly relevant to Information Security and Computational Architectures.
• Domain Expertise: Prior professional engagement within high-performance computing, quantitative environments, advanced technology sectors, or specialized DevSecOps environments is highly advantageous.
• Quantitative & Technical Literacy: Deep comfort with information security fundamentals, common attack vectors, and the operational rigor inherent in a firm focused on supercomputing and high-speed data processing.

• Base Salary: $250,000-$800,000 (Determined based on the nature/extent of prior experience and educational background).
• Additional Compensation: Sign-on and year-end bonuses, alongside generous benefits (including relocation and immigration assistance).
• Work Schedule: Hybrid (In-office Tuesday through Thursday; optional remote Monday and Friday).