Principal Data Scientist

If you are a current Jazz employee please apply via the Internal Career site., Location: This role can be based either in Cambridge or Kent Science Park, SittingbourneJob Role:We are looking for dynamic, creative, and talented computational chemist to join our expanding Discovery & Medicinal Chemistry Department. Reporting to the Director of Medicinal Chemistry, you will apply your expertise, leadership and guidance to discover and develop novel small-molecule therapeutic agents. You will be working within a patient-focused, science-driven, and multi-disciplinary biopharmaceutical environment, covering all stages of the drug discovery process. You will collaborate with scientists from other disciplines within Jazz Pharmaceuticals and with external collaborators to build an innovative portfolio of therapeutics across our exciting and growing oncology and neuroscience pipelines. Working at the forefront of drug discovery you will advance projects from target selection to preclinical drug candidates and Fi H trials, and contribute to the growth of the medicinal chemistry team.Key Responsibilities:Utilize modern molecular modelling methods to support different stages of R&D programs.Collaborate effectively with other departments and functions to advance research discovery projects expeditiously from hit identification to high quality preclinical candidates.Design, lead and drive computational studies on projects throughout the several discovery phases and ensure execution on agreed deliverables.Opportunities to lead or co-lead projects in addition to drive discipline-specific endeavours.Set the vision and strategy for computational chemistry.Foster innovative thinking in all areas of departmental activities, with a particular focus on computational and medicinal chemistry.Manage CRO compchem activities, providing expertise and guidance.Present plans and results internally, including at board level, and externally at conferences.Contribute to the writing of patent applications, scientific publications, and internal reports.Develop and mentor less experienced staff.Keep up to date with the latest scientific advances and trends in drug discovery to deliver the next-generation therapies.Undertake ongoing professional development by attending relevant training and conferences., Snapshot As a Chemist in the Responsible Development & Innovation (ReDI) team at Google DeepMind, you will be a principal architect of the safety protocols governing the intersection of Large Language Models (LLMs) and the chemical sciences. You will design and execute..., A pioneering biotech firm in Greater London is seeking a Senior / Principal Data Scientist to develop AI systems that drive scientific discovery. You will work in an interdisciplinary environment focusing on large language models and machine learning, translating complex...

Requirements & Qualifications:MSc/Ph D in a relevant scientific discipline (Pharmaceutical Sciences, Chemistry, Computational Chemistry) with a solid foundation in molecular modelling built in a pharma/biotech/CRO setting.Expert knowledge in CADD software packages and modern molecular modelling techniques.Sound knowledge in cutting-edge cheminformatic tools, AI/ML-enabled technologies, and in silico drug design, including both structure- and ligand-based methodologies.Passion for drug discovery with a deep entrepreneurial and problem-solving attitude.Mastery of all the theoretical and practical principles of medicinal chemistry and drug design.Broad knowledge of biophysical, biochemical, and cell-based assays used in the early stages of the drug discovery process.In depth understanding of multi-parameter optimization and ability to integrate disease biology, ADME/DMPK and toxicology data to solve complex drug discovery problems.Excellent leadership, management, organizational and team-working skills, and a talent to deliver project milestones within the expected time frame.Demonstrated track record of scientific publications.Exceptional oral, written, and interpersonal communication skills, and ability to develop and grow strong cross-functional collaborations.

The successful candidate will also be eligible to participate in various benefits offerings, including, but not limited to, medical, dental and vision insurance, retirement savings plan, and flexible paid vacation. For more information on our Benefits offerings please click here: https://careers.jazzpharma.com/benefits.html . Similar jobs

Jazz Pharmaceuticals is a global biopharma company whose purpose is to innovate totransform the lives of patients and their families. We are dedicated to developinglife-changing medicines for people with serious diseases - often with limited or notherapeutic options. We have a diverse portfolio of marketed medicines, including leadingtherapies for sleep disorders and epilepsy, and a growing portfolio of cancer treatments.Our patient-focused and science-driven approach powers pioneering research and developmentadvancements across our robust pipeline of innovative therapeutics in oncology andneuroscience. Jazz is headquartered in Dublin, Ireland with research and developmentlaboratories, manufacturing facilities and employees in multiple countries committed toserving patients worldwide. Please visitwww.jazzpharmaceuticals.comfor more information., Principal Consultant - Applied and Computational Sciences Capgemini Engineering, the world leader in engineering services, brings together a global team of engineers, scientists, and architects to help the world's most innovative companies unleash their potential. From..., Bitsight is a cyber risk management leader transforming how companies manage exposure, performance, and risk for themselves and their third parties. Companies rely on Bitsight to prioritize their cybersecurity investments, build greater trust within their ecosystem, and..., Join us at Entrust At Entrust, we're shaping the future of identity centric security solutions. From our comprehensive portfolio of solutions to our flexible, global workplace, we empower careers, foster collaboration, and build solutions that help keep the world moving..., Job Description NBCUniversal, the global media company that brought you some of the world's most iconic television and film franchises, including: The Tonight Show, Saturday Night Live, Keeping Up With The Kardashians, The Real Housewives, Mr. Robot, The Voice, This Is Us,...