Senior Scientist (Computational Genomics & Large-Scale Molecular Data Analysis) - Neurology

We are seeking a highly motivated Staff Scientist to lead and support the analysis of large-scale molecular datasets in a dynamic, collaborative research environment. This role focuses on cutting-edge functional genomics, with an emphasis on single-cell and multi-omic technologies.

The Staff Scientist will drive computational analysis of high-dimensional datasets, partnering closely with a well-integrated computational-experimental team to generate biological insights from complex genomic data. The ideal candidate has deep expertise in single-cell transcriptomics and epigenomics, experience handling large-scale datasets, and strong quantitative and programming skills. Experience in machine learning and AI approaches is highly desirable.

• Ph.D in sciences or related field
• Minimum five years of experience with scientific investigation.
• Must have demonstrated outstanding achievement in a field of research
• Must have contributed to a number of peer-reviewed publications, inventions or the like, at least some of which have had a major impact on advancing the field or discipline.
• Prior experience successfully securing external grant funding is highly desirable.

Preferred Skills

• PhD in Computational Biology, Bioinformatics, Genomics, Statistics, Computer Science, or related field (or equivalent experience).
• Strong experience analyzing bulk and single-cell RNA-seq and epigenomic data.
• Proficiency in R, including common single-cell analysis frameworks.
• Experience working with large-scale genomic datasets and high-performance computing environments.
• Strong statistical background and data visualization skills.
• Experience analyzing DNA methylation data (e.g., array-based or sequencing-based approaches).
• Experience analyzing long-read RNA sequencing datasets.
• Demonstrated use of machine learning/AI methods for genomic data integration or prediction.
• Familiarity with cloud-based workflows and reproducible pipeline development.
• Track record of publications in peer-reviewed journals.

The Mount Sinai Health System (MSHS) provides salary ranges that comply with the New York City Law on Salary Transparency in Job Advertisements. The salary range for the role is $58,661.00 - $125,008.22 Annually. Actual salaries depend on a variety of factors, including experience, education, and operational need. The salary range or contractual rate listed does not include bonuses/incentive, differential pay or other forms of compensation or benefits.