Cell Line Development

As a Cell Line Development Scientist, you will play a critical role in establishing high-performing mammalian cell lines that enable early-phase biologics programs. This position offers the opportunity to shape foundational capabilities in a fast-paced, collaborative environment focused on innovation and client success.

• Design and execute strategies for stable cell line development using CHO cell line systems.
• Perform hands-on CHO cell line development and characterization studies, including transfection, selection, single cell subcloning, growth and productivity screening, cell banking and stability assessment of cell banks.
• Culture mammalian cells across multiple scales and formats, from 96-well plates up to large shake flasks, experience with ambr 250 and bioreactors is ideal.
• Implement high-throughput screening and automation tools for clone evaluation.
• Maintain rigorous documentation and ensure compliance with quality and regulatory standards.
• Author and review cell line development reports, summaries, and presentations.
• Present updates at client and cross-functional meetings.
• Partner with Upstream and Downstream Process Development and Analytical teams to deliver integrated solutions.
• Contribute to technology evaluations and continuous improvement initiatives for cell line workflows.

• M.S. in Cell Biology, Molecular Biology, Biochemistry, or related field.
• 2-5 years of industry experience in cell development for biologics.
• Hands-on experience with CHO cell systems, transfection methods, and clone screening for production of monoclonal antibodies, antibody-like molecules, enzymes, cytokines, bi-specifics and other recombinant molecules.
• Strong knowledge of mammalian cell culture, molecular biology techniques and bio process engineering concepts.
• Proficient in aseptic mammalian cell culture techniques.
• Familiarity with automation platforms and data analysis tools.
• Excellent problem-solving and communication skills.