Director, Enterprise Applications, IT (Business Systems)

IDEAYA Biosciences is seeking a Director, Enterprise Applications, IT (Business Systems) to lead the strategy, delivery, and operations of enterprise applications supporting both Research & Development and General & Administrative functions.

This role is responsible for building and operating a scalable, compliant, and integrated enterprise application ecosystem spanning Research, Clinical, DevOps, Supply Chain, Finance, HR and Legal systems. The Director will act as a key IT Business partner to R&D and G&A leadership, translating enterprise priorities into technology roadmaps and delivering systems that enable operational efficiency, compliance, and data-driven decision-making.

This leader will oversee enterprise platforms, system integrations, vendor ecosystems, and digital transformation initiatives across both regulated (GxP, SOX) and non-regulated enterprise domains, ensuring alignment with IDEAYA's growth as a commercial-stage biotechnology company.

This position is based in South San Francisco and requires onsite presence four days per week per company policy., * Lead the strategy, design, implementation, and operations of enterprise applications supporting R&D (Clinical, Regulatory) and G&A (Finance, HR, Legal, Procurement) functions.

• Define and maintain enterprise application roadmaps aligned with business strategy, operational priorities, and compliance requirements.
• Oversee implementation and lifecycle management of systems such as Veeva (EDC/RIM/eTMF/QMS), NetSuite, Workday, Coupa, ADP, Concur, and CLMS platforms (e.g., Ironclad).
• Lead enterprise system integration strategy across R&D and G&A platforms, ensuring seamless data flow and interoperability across applications.
• Drive end-to-end execution of system implementations, enhancements, upgrades, and migrations across enterprise applications.
• Establish governance frameworks, steering committees, and prioritization processes across R&D and G&A stakeholders.
• Manage vendor ecosystem including SaaS providers, system integrators, and managed service providers (MSPs), ensuring delivery accountability and performance.
• Oversight of other IT Project Managers, vendors, and managed service providers (MSPs) to deliver projects with quality and high customer satisfaction. This includes securing funding and approvals, managing resource allocation, and implementing robust governance through change control policies, executive dashboards, and centralized program and portfolio management.
• Ensure compliance with regulatory and financial frameworks including GxP, CSA/CSV, 21 CFR Part 11, Annex 11, SOX, ITGC, and other internal control standards.
• Drive system validation and support audit readiness/inspection activities across regulated and enterprise applications.
• Lead organizational change management, user adoption, and training initiatives to ensure successful system deployment and utilization.
• Develop executive dashboards and portfolio reporting to enable transparency into enterprise IT investments and initiatives.
• Continuously evaluate emerging technologies, including cloud platforms, automation, and AI-driven enterprise applications, to improve efficiency and IT Capabilities., The expected salary range for the roleof Director, Enterprise Applications, IT (Business Systems) is $209,000 - $258,000. The final salary offered to a successful candidate will depend on several factors that may include but are not limited to the office location where this open position is located, the final candidates' experience within their profession, experience in the disease areas we are striving to make an impact in as a company, length of time within the industry, educational background, and performance during the interview process.

The Company complies with all laws respecting equal employment opportunities and does not discriminate against applicants with regard to any protected characteristic as defined by federal, state, and local law. This position requires you to work onsite in the office at the Company's facilities for training & meetings, with work-from-home flexibility, and the Company requires that all employees working in its facilities be fully vaccinated (except as required by applicable law). Therefore, this position requires you to be fully vaccinated from COVID-19, subject to reasonable accommodations for medical or religious reasons, and/or as otherwise required by applicable law. The Company considers you fully vaccinated once 14 days have passed since you received either the second dose in a two-dose COVID-19 vaccine series or a single-dose COVID-19 vaccine. The vaccine must have been FDA approved, have emergency use authorization from the FDA, or, for persons fully vaccinated outside of the U.S., be listed for emergency use by the World Health Organization.

IDEAYA is an equal opportunity employer. In accordance with applicable law, IDEAYA does not discriminate in hiring or otherwise in employment based on race, color, religion, sex, national origin, age, marital or veteran status, disability, sexual orientation, or any other legally protected status. EOE/AA/Vets.

We are committed to providing reasonable accommodations to qualified individuals with disabilities. If you need assistance or an accommodation due to a disability, please get in touch with us at hr@ideayabio.com.

• Bachelor's degree in Information Systems, Computer Science, Engineering, or related field; advanced degree preferred.
• 12-15+ years of IT experience, including 10+ years of leadership experience across enterprise applications.
• Strong business process expertise across R&D and enterprise functions (Clinical, Regulatory, Finance, HR, Legal, Procurement) in life sciences or biotech environments.
• Hands-on experience with enterprise platforms including SAS, clinical data warehouses, Veeva (RIM, eTMF, QMS), Workday, NetSuite, Coupa, ADP, Concur, CLM systems (e.g., Ironclad), and Smartsheet.
• Strong understanding of system integration, enterprise architecture, and cloud-based SaaS ecosystems.
• Strong knowledge of regulated environments including GxP, 21 CFR Part 11, Annex 11, SOX, ITGC, and validation lifecycle frameworks.
• Experience driving governance, portfolio management, and enterprise IT operating models.
• Demonstrated success leading high performance IT teams, managing vendors, and delivering enterprise-scale programs.
• Strong understanding of cloud architecture, integration frameworks, and data platforms.

Hands-on leadership style with strong analytical thinking, judgment, and execution capability.

All employees are expected to act with integrity and in full compliance with applicable laws, regulations, and IDEAYA policies, including IDEAYA's Code of Conduct.

Employees must demonstrate good judgement and ethical behavior in all business activities, maintain patient and product safety as a top priority, and report any suspected violations of law or Company policy through appropriate channels

Along with our inspiring mission, and highly collaborative and inclusive environment, IDEAYA offers a competitive total rewards package that reflects our pay-for-performance philosophy where employees are eligible to be considered for merit-based salary increases, company discretionary short-term incentive plan participation, and company discretionary stock option awards (based on board approval). Our comprehensive benefits package includes, but is not limited to, medical/dental/vision coverage (100% company paid for employees and 90% company paid for dependents), 401k, ESPP, and wellness programs.

When you're at IDEAYA, you will be in the midst of brilliant minds working on precision medicine therapies to help cancer patients. We are passionate and committed about being on the forefront of oncology medicine, which means we all have a high internal drive that is at the very core of every person at IDEAYA. We are inquisitive, ask deep questions, and are data-driven innovators who like to collaborate and use team work to move science forward. For more information, please see www.ideayabio.com., Founded in 2015, IDEAYA Biosciences is a public, clinical-stage synthetic lethality-focused precision medicine oncology company committed to the discovery and development of targeted therapeutics for patient populations selected using DNA sequencing and other molecular diagnostics. Our approach integrates extensive capabilities in identifying and validating translational biomarkers with small molecule drug discovery to select patient populations most likely to benefit from the therapies we are developing. We are applying these capabilities across multiple classes of precision medicine, including direct targeting of oncogenic pathways and synthetic lethality - which represents an emerging class of precision medicine targets. We believe this diversified approach will enable us to deliver the right medicine to the right patient to drive a more robust clinical response.