Staff, Bioinformatics Data Scientist

• Design and implement analyses across Rezo’s protein network datasets, refining existing approaches and developing new methods as needed.
• Integrate multi-omics data to build mechanistic and translational understanding of our programs, spanning from mechanism of action to patient biomarker selection strategies.
• Build internal tools and interfaces that enable the rest of the company to explore the data and make decisions based on conducted analyses.
• Familiar with ML methods, including interpreting results and experience curating data for ML methods.
• Communicate results clearly in writing, figures and presentations so that the analyses can be translated into program decisions.

• PhD in computational biology, bioinformatics, systems biology, cancer biology or related field with 8+ years of industry experience.
• Deep experience analyzing at least three of the following -omic datasets: transcriptomics, proteomics and their variants (e.g. phosphoproteomics, etc.), AP-MS / interactomic data and functional genomics (e.g. DepMap, CRISPR screens).
• Strong python engineering skills. Comfortable working in a shared codebase and using software engineering best practices, including code reviews.
• Clear demonstrations of the ability to take a biological question from raw data to a concrete mechanistic or translational conclusion.
• Working fluency in cancer biology, including oncogenic signaling, tumor suppressors, cell cycle and the use of biomarker classification to distinguish sensitive versus resistant populations.
• Proven ability to work independently while fostering collaboration in a team environment.
• Excellent organizational, communication, and interpersonal skills. Compensation at Rezo

The expected starting salary range for this position based in San Francisco, California for Staff/Senior Staff level is $180,000-$260,000. Actual starting salary will be determined based on multiple job-related factors including candidate’s skills, education, and experience, the level at which they are hired, market demand, business needs, and internal parity. This role is eligible for participation in our Annual Discretionary Bonus Plan (based on individual and company performance) and our Equity Incentive Plan, subject to the terms of those plans and associated policies. This position is also eligible for the benefits detailed below.

Rezo is a different kind of biopharma company. Our mission is to dramatically increase the success rate of drug development by building a disease-agnostic, fully-integrated, network biology platform that will redefine our understanding of human disease and ability to treat it. We are leveraging a unique integrated approach, combining capabilities in genetics, proteomics, structural biology and AI to generate deep biological insights and novel therapeutic approaches.