Technical Lead

Oncology Research Advising Equities Kubeflow Genomics DevSecOps LangChain Leadership Consulting Governance Innovation Kubernetes Mitigation TensorFlow Ontologies Scalability Informatics Market Data Data Science Communication Life Sciences Deep Learning Cyber Security Graph Database Bioinformatics Responsible AI Clinical Trials Microsoft Azure Problem Solving Data Management Computer Vision Cloud Computing Semantic Search Vector Database Customer Service Computer Science Machine Learning Medical Research Clinical Research Influencing Skills Operationalization Technical Strategy Customer Engagement Amazon Web Services Technology Roadmaps Applied Mathematics Multi-Agent Systems Software Engineering Software Development Knowledge Management Computer Engineering Lifecycle Management Technical Leadership Predictive Analytics Scientific Computing Explainable AI (XAI) Emerging Technologies Technology Strategies Computational Biology Information Technology Cloud-Native Computing Operational Efficiency Biomedical Informatics Artificial Intelligence Enterprise Architecture Large Language Modeling Software Technical Review Clinical Decision Support Semantic Interoperability High Performance Computing Google Cloud Platform (GCP) Hugging Face (NLP Framework) Artificial Intelligence Risk Scikit-Learn (Python Package) Cross-Functional Team Leadership Artificial Intelligence Strategy Natural Language Processing (NLP) Generative Artificial Intelligence PyTorch (Machine Learning Library) MLOps (Machine Learning Operations) Artificial Intelligence Infrastructure, The Leidos Health & Civil Sector is seeking a Technical Lead to support the National Institutes of Health (NIH), National Cancer Institute (NCI), Center for Biomedical Informatics and Information Technology (CBIIT) Business Information Technology Solutions Development and Integration Services (BITSDIS) 2 program.

** This posting is for future business - not yet awarded **

The Technical Lead will provide strategic technical leadership, scientific consulting, and executive-level advisory support to Government leadership for the development, integration, and operationalization of advanced Artificial Intelligence (AI), Machine Learning (ML), and data science capabilities that accelerate cancer research, clinical decision support, and precision medicine.

Serving as the Government’s trusted technical advisor, the Technical Lead will collaborate closely with NCI leadership, principal investigators, biomedical researchers, clinicians, informaticians, and multidisciplinary engineering teams to develop innovative AI-enabled solutions supporting clinical research, scientific data management, and enterprise research platforms.

The successful candidate will combine deep expertise in artificial intelligence, machine learning, biomedical informatics, cloud computing, and modern software engineering with exceptional customer engagement and communication skills to guide technology strategy, influence architectural decisions, and ensure delivery of scalable, secure, and scientifically rigorous AI capabilities aligned with NIH and NCI strategic priorities., * Lead the technical strategy, architecture, and implementation of AI-enabled solutions that support cancer research, precision medicine, clinical research, and enterprise biomedical informatics.

• Serve as the principal technical advisor to NCI leadership, providing strategic guidance on AI, ML, biomedical informatics, and digital modernization initiatives.
• Partner with Government stakeholders, scientific leadership, and multidisciplinary Subject Matter Experts (SMEs) to define technical priorities, evaluate emerging technologies, and deliver innovative, mission-focused solutions.
• Provide technical leadership across AI model development, deployment, and lifecycle management, including machine learning, deep learning, natural language processing (NLP), large language models (LLMs), computer vision, predictive analytics, and multi-agent AI systems.
• Oversee the design and integration of AI capabilities supporting biomedical imaging, radiomics, genomics, multi-omics analysis, precision oncology, clinical trial optimization, semantic search, knowledge management, and decision support.
• Guide the development of scalable AI and cloud-based architectures leveraging high-performance computing (HPC), AWS, Azure, Google Cloud Platform, Kubernetes, and modern MLOps practices.
• Ensure AI solutions adhere to Responsible AI principles, including model governance, explainability (XAI), bias mitigation, security, privacy, and compliance with NIH policies, Executive Orders, and the NIST AI Risk Management Framework.
• Lead technical reviews, architecture discussions, executive briefings, and technology roadmaps while effectively communicating complex technical concepts to Government executives, researchers, and business stakeholders.
• Mentor engineering teams and provide technical oversight to AI engineers, software developers, data scientists, cloud architects, cybersecurity specialists, and biomedical informatics SMEs to ensure successful delivery of high-quality technical solutions.
• Evaluate and recommend emerging AI technologies and innovative approaches that accelerate scientific discovery, improve operational efficiency, and advance NCI’s strategic research mission., Gitlab OpenAI Jupyter PySpark Equities Operations Management Governance Kubernetes Market Data AWS Amplify AWS Bedrock Data Modeling Elasticsearch AWS SageMaker Version Control Ancient History Agile Methodology Docker (Software) Workflow Management Atlassian Confluence Cloud-Native Computing Artificial Intelligence Research And Development Internet Of Things (IoT) Java (Programming Language) Computer Network Operations Git (Version Control System) Scrum (Software Development) Hugging Face (NLP Framework) React.js (Javascript Library) Python (Programming Language) Front End (Software Engineering) Object-Oriented Programming (OOP) Amazon Elastic Kubernetes Service Application Programming Interface (API) Top Secret-Sensitive Compartmented Information (TS/SCI Clearance) +0 Senior Artificial Intelligence (AI) Engineer (SWE-3) Leidos

Odenton, MD*On-Site

JIRA Gitlab OpenAI Jupyter PySpark Equities Operations Management Governance Kubernetes Market Data AWS Amplify AWS Bedrock Data Modeling Elasticsearch AWS SageMaker Version Control Ancient History Agile Methodology Docker (Software) Workflow Management Atlassian Confluence Cloud-Native Computing Artificial Intelligence Research And Development Internet Of Things (IoT) Java (Programming Language) Computer Network Operations Git (Version Control System) Scrum (Software Development) Hugging Face (NLP Framework) React.js (Javascript Library) Python (Programming Language) Front End (Software Engineering) Object-Oriented Programming (OOP) Amazon Elastic Kubernetes Service Application Programming Interface (API) Top Secret-Sensitive Compartmented Information (TS/SCI Clearance) +0 Data Scientist, Sr - Artificial Intelligence, Cloud & Automation (Open) Leidos

Ft Meade, MD*On-Site

Planning Equities Timelines Terraform Hardening AI Agents Operations Leadership Management Automation Resilience Kubernetes Agentic AI Market Data Data Science Data Pipelines Microsoft Azure Law Enforcement Machine Learning Cloud Operations Cyber Operations Computer Networks Cyber Engineering Workflow Management Amazon Web Services Technology Transfer GIAC Certifications SQL And Java (SQLJ) Software Development Operational Planning Intelligence Gathering Artificial Intelligence Certified Ethical Hacker Computer Network Defense IAT Level II Certification Infrastructure as Code (IaC) Python (Programming Language) GIAC Certified Incident Handler Artificial Intelligence Strategy Certified Information Systems Security Professional Top Secret-Sensitive Compartmented Information (TS/SCI Clearance) +0 Login | JoinContact

• Master’s degree in Computer Science, Artificial Intelligence, Biomedical Informatics, Bioinformatics, Data Science, Computer Engineering, Applied Mathematics, or a related discipline.
• Minimum 15 years of progressively responsible technical leadership supporting large-scale Federal health, biomedical research, or scientific computing programs.
• Minimum 10 years designing, implementing, and leading enterprise AI and ML solutions within healthcare, biomedical research, life sciences or federal research environments.
• Demonstrated experience supporting NIH, NCI, or other Federal biomedical research organizations.
• Extensive expertise in deep learning, machine learning, generative AI, NLP, LLMs, computer vision, predictive analytics, biomedical informatics, and cloud-native AI architectures.
• Demonstrated experience advising executive Government customers on AI strategy, enterprise architecture, and digital modernization initiatives.
• Proven experience leading multidisciplinary teams consisting of AI engineers, data scientists, software engineers, cloud architects, cybersecurity specialists, and biomedical subject matter experts.
• Experience with HPC, cloud-native AI platforms, Kubernetes, DevSecOps, and MLOps.
• Familiarity with TensorFlow, PyTorch, Scikit-learn, Hugging Face, MLflow, Kubeflow, LangChain, vector databases, graph databases, and AI orchestration frameworks.
• Ability to obtain and maintain a Public Trust / ADPII Clearance.

Preferred Qualifications

• Ph.D. in AI, Biomedical Informatics, Computer Science, Computational Biology, or related field preferred.
• Experience supporting NCI organizations including CBIIT, CCR, DCTD, DCP, or related biomedical research programs.
• Experience with cancer informatics, biomedical imaging, radiomics, genomics, precision oncology, clinical trials, and translational research.
• Expertise with FHIR, OMOP, FAIR data principles, biomedical ontologies, semantic interoperability, and research data ecosystems., * Strong customer focus and mission orientation.
• Excellent analytical and problem-solving skills.
• Ability to lead cross-functional teams in a collaborative environment.
• Commitment to quality, innovation, and continuous process improvement.
• Ability to communicate effectively with both technical and executive audiences

If you’re looking for comfort, keep scrolling. At Leidos, we outthink, outbuild, and outpace the status quo - because the mission demands it. We’re not hiring followers. We’re recruiting the ones who disrupt, provoke, and refuse to fail. Step 10 is ancient history. We’re already at step 30 - and moving faster than anyone else dares.

Pay and benefits are fundamental to any career decision. That’s why we craft compensation packages that reflect the importance of the work we do for our customers. Employment benefits include competitive compensation, Health and Wellness programs, Income Protection, Paid Leave and Retirement. More details are available at www.leidos.com/careers/pay-benefits .

Leidos is an industry and technology leader serving government and commercial customers with smarter, more efficient digital and mission innovations. Headquartered in Reston, Virginia, with 47,000 global employees, Leidos reported annual revenues of approximately $16.7 billion for the fiscal year ended January 3, 2025. For more information, visit www.Leidos.com .