Senior Manager, Data Sciences

Bristol-Myers Squibb Company
Uxbridge, UK
2 days ago
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Role details

Contract type
Permanent contract
Employment type
Full-time (> 32 hours)
Experience level
Expert
Experience required
1 year minimum
Compensation
£72,511.0
Working hours
Regular working hours

Tech stack

Artificial Intelligence Amazon Web Services Microsoft Azure Big Data Cloud Computing Code Review Computational Biology Information Engineering Data Governance Data Presentation EHealth R (Programming Language)
+9 more
Python (Programming Language) Machine Learning SQL Databases Explainable AI (XAI) Deep Learning Model Validation Electronic Medical Records Information Technology Databricks

Job description

  • Execute data science analyses on datasets from BMS clinical trials and real-world data cohorts, spanning genomics, proteomics, imaging, flow cytometry, and other high-dimensional biomarker data types
  • Develop innovative approaches to integrating, mining, and visualising diverse, high-dimensional, and disparate datasets generated across early-to-late phase drug development
  • Formulate, implement, test, and validate predictive models and build efficient, automated processes for delivering modelling results at scale
  • Apply modern machine learning capabilities - including AI/ML, deep learning, NLP, causal ML, and explainable AI - across multiple data modalities and clinical development contexts
  • Apply statistically rigorous approaches to clinical trial data, including survival analysis, longitudinal/mixed-effects modelling, and appropriate handling of missing data and censoring
  • Contribute to the scientific and statistical strategy of drug development programs, including the development of predictive biomarkers, novel trial designs, and precision medicine approaches

Data Engineering & Reproducibility

  • Build and maintain well-structured, reproducible, version-controlled analytical pipelines and codebases using Python, R, SQL, and cloud platforms
  • Develop and apply data quality frameworks to assess and ensure fitness-for-purpose of diverse data sources for specific analytical questions
  • Implement strong model evaluation practices including cross-validation strategies, calibration assessment, and transparent reporting of model performance and limitations
  • Build scalable, automated processes for delivering analytical results across multiple programs and data types

Collaboration & Technical Contribution

  • Partner with lead and protocol statisticians in contributing to statistical analysis plans (SAPs) for exploratory data science analyses supporting drug development programs
  • Collaborate with cross-functional teams including clinicians, translational medicine scientists, biostatisticians, data engineers, and IT/engineering professionals
  • Contribute to team excellence through code reviews, technical mentorship, and raising the overall engineering and methodological standards of the team
  • Communicate analytical strategies and results clearly and effectively to both technical and non-technical stakeholders, with strong data presentation and visualisation skills
  • Manage and coordinate deliverables across concurrent, fast-paced projects within tight timelines, Where you work matters - because collaboration, innovation and patient impact happen in many settings. Our roles are structured across four work models: site-essential, site-by-design, field-based and remote-by-design. The model assigned to this role is based on its core responsibilities. Learn more at https://careers.bms.com/ways-of-working.

Supporting People with Disabilities

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

Requirements

  • PhD in a relevant quantitative field (e.g., Computational Biology, Biostatistics, Statistics, Biomedical Engineering, or Computer Science) with 1+ years of academic/industry experience; or a Master’s Degree in a relevant quantitative field with 3+ years of industry experience
  • Strong experience in data science and statistical analysis using clinical trial or electronic health records data, particularly in a pharma R&D context
  • Experience developing and validating statistical and machine learning models on high-dimensional data for time-to-event, longitudinal, and multivariate outcomes
  • Experience in the application of AI/ML and proficiency in Python, R, SQL, and cloud platforms (e.g., AWS, Azure, Databricks)
  • Familiarity with clinical trial design, drug development processes, and the role of biomarkers in regulatory and clinical decision-making
  • A perspective on leveraging innovative approaches to expedite drug development and address the complexities of emerging data types
  • Strong problem-solving, collaboration, and communication skills, with the ability to handle several concurrent, fast-paced projects independently and as part of a team, * Experience with genomics, proteomics, imaging, flow cytometry, or immunobiology datasets from clinical trials
  • Experience with NLP, causal ML, explainable AI, and survival analysis/time-to-event modelling
  • Knowledge of molecular biology and understanding of disease pathways
  • Experience with real-world data (RWD/RWE) sources and associated analytical methods
  • Familiarity with digital health data and wearable/sensor-derived data types
  • Experience with cloud-based scalable compute and deployment patterns for large-scale data processing and model training

Benefits & conditions

£72,511 per year - estimated ? Full time NEW

At Bristol Myers Squibb, our employees often ask, “Who are you working for?”-a question that fuels collaboration, accountability, and urgency in our work. Our purpose-driven culture inspires us to discover, develop, and deliver innovative medicines to prevail over serious diseases. We offer uniquely interesting and meaningful work, opportunities for growth, and a supportive environment that values inclusion, wellbeing, flexibility, and comprehensive benefits. This is work that transforms the lives of patients, and the careers of those who do it.

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