Partner - Data Management, Architecture & Analytics Products

Roche
Basel, Switzerland
4 days ago

Role details

Contract type
Temporary contract
Employment type
Full-time (> 32 hours)
Working hours
Regular working hours
Languages
English, German
Compensation
CHF 208K

Job location

Basel, Switzerland

Tech stack

Data analysis
Data Visualization
R
Python
JMP (Statistical Software)
Data Management
Spotfire

Job description

The Process Chemistry & Catalysis (PTDC-C) team is dedicated to designing and developing robust and cost-effective drug substance processes using state-of-the-art science and methodologies. Our critical work supports the synthetic molecules portfolio from the initial entry into human trials through the transfer to commercial manufacturing, including the necessary support for regulatory submissions. We are a key part of Small Molecules Technical Development (PTDC), which develops our synthetic pipeline and manufactures drug substance and drug product for clinical studies, collaborating closely with research partners and the commercial manufacturing network., * Drive the day-to-day execution of HTE campaigns for chemical reaction screening and optimization, ensuring the operational excellence and reliability of automated laboratory systems.

  • Execute and optimize a wide range of chemical experiments, from milligram to decagram scale, including reactions under pressure, utilizing advanced robotic and automation platforms.
  • Collaborate closely with chemistry project teams on experimental design, contributing to rigorous data analysis, documentation, and interpretation of screening results.
  • Act as a "super-user" and first point of contact for operational issues, maintaining and troubleshooting state-of-the-art HTE instrumentation (e.g., solid dispensers, reaction execution platforms, liquid handlers, parallel autoclaves).
  • Contribute to the continuous improvement of automation workflows by evaluating new technologies, identifying bottlenecks, and optimizing protocols for efficiency, robustness, and data quality.
  • Support the training and supervision of junior associates or interns, actively promoting a culture of safety, precision, and collaboration.
  • Ensure all work is meticulously documented, analyzed, and presented to project teams.

Requirements

Do you have a Master's degree?, * Hold a Degree in Chemistry or Chemical Engineering and possess a minimum of 2 years (with Master's) or 4 years (with Bachelor's) of relevant industrial or academic experience, preferably in process chemistry, catalysis, or pharmaceutical development.

  • Demonstrated hands-on experience with automated laboratory equipment (e.g., liquid handlers, automated synthesis platforms) and a strong foundational knowledge of organic chemistry and chemical reaction optimization. Direct experience in a HTE setting is a plus.
  • A natural problem-solver with excellent organizational skills, a proven ability to manage complex experimental plans, analyze data, and maintain meticulous documentation.
  • Experience with statistical Design of Experiments (DoE) principles/software (e.g., JMP) or proficiency with data analysis and visualization tools (e.g., Python, R, Spotfire) is preferred.
  • Possess strong collaboration and interpersonal skills, with fluency in English (written and spoken). Fluency in German is a plus.

About the company

A healthier future drives us to innovate. Together, more than 100'000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact. Let's build a healthier future, together. Roche is an Equal Opportunity Employer.   You must create an Indeed account before continuing to the company website to apply

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