Head of PPA, External Data and AI Workflows

Strategic Leadership

• Own the strategy and vision for both PPA and External Data domains, ensuring high-quality, harmonized, AI-ready data throughout the portfolio lifecycle.
• Align product strategy with R&D leadership priorities, portfolio review processes, and investment decision bodies.
• Lead development of executive-level dashboards and insights leveraging Planisware, Enrich, and Veeva Vault RIM.
• Drive integration of AI-powered portfolio optimization, predictive modeling, and real-time competitive intelligence.
• Define and monitor KPIs related to pipeline health, attrition, progression, and portfolio value, incorporating AI-generated predictive risk metrics.
• Lead quarterly/annual planning and prioritization based on scientific value, business impact, and AI/ML maturity.

Project & Pipeline Analytics (PPA) Product Management

• Oversee delivery and continuous improvement of PPA systems including pipeline tracking, stage-gate milestones, asset valuation/NPV modeling, and portfolio simulation tools.
• Integrate data across R&D systems (clinical, regulatory, competitive intelligence) into unified portfolio views.
• Lead development of ML models for drug discovery prediction, PTS scoring, clinical outcome prediction, and indication prioritization.
• Champion data standards and interoperability frameworks (CDISC, OMOP, FAIR).
• Drive adoption of automated data quality monitoring, anomaly detection, and NLP tools for literature and regulatory document mining.

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External Data Sharing Platform Management

• Own the end-to-end lifecycle of external data sharing platforms from ingestion and transformation to partner provisioning and governance.
• Operationalize and enforce DUAs, access controls, and compliance policies in partnership with legal, privacy, and compliance teams.
• Manage relationships with academic institutions, CROs, health systems, and government agencies, ensuring SLA adherence and data quality.
• Oversee secure data enclaves, TREs, and controlled-access environments aligned with industry frameworks (YODA, CSDR, Project Data Sphere).
• Drive adoption of federated learning, de-identification pipelines, tokenization, and full auditability.
• Ensure global regulatory compliance (ICH E17, GDPR Article 46).
• Expand Sanofi's external data ecosystem through consortium partnerships (IMI, OHDSI, FDA Sentinel).

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Product Management & Delivery Excellence

• Lead a team of Data and AI Product Owners delivering PPA and external data products, including AI/ML-powered capabilities.
• Manage cross-product dependencies to ensure governance alignment, interoperability, and high data quality.
• Ensure adherence to FAIR data principles, CI/CD, MLOps, and audit-ready development practices.
• Build shared services across teams including reusable data assets, metadata catalogs, and shared ML model repositories.
• Own AI model lifecycle management including versioning, monitoring, drift detection, and continuous retraining.
• Measure product impact across business KPIs, AI model performance, pipeline metrics, and end-user satisfaction.

Team Leadership

• Build, mentor, and scale a high-performing team of Product Owners and analysts, including AI/ML specialists.
• Foster a culture of accountability, innovation, agility, and responsible AI.
• Establish success metrics, conduct performance reviews, and develop team capabilities across product, data, and AI disciplines.

• Bachelors required, Master's or Ph.D strongly preferred.
• 8+ years of product leadership experience, including 5+ years in life sciences or clinical research portfolios.
• Proven track record building and developing high-performing product teams, including AI/ML specialists.
• Exceptional communication and executive stakeholder management experience.

Domain Expertise

Pipeline Analytics & Portfolio Management

• Deep expertise with Planisware, Enrich, Veeva Vault RIM, stage-gate tracking, and valuation platforms.
• Experience translating complex pipeline data into dashboards and KPIs supporting executive decisions.
• Strong understanding of drug development (IND ? post-market) and its data requirements.
• Experience unifying diverse R&D data sources to support portfolio review committees and decision-support analytics.

External Data Sharing

• Hands-on experience designing and managing external data sharing platforms, DUAs, and partner governance.
• Proven experience partnering with academic, CRO, health system, and government stakeholders.
• Expertise with TREs, secure enclaves, controlled-access platforms, and patient-level data sharing frameworks.
• Knowledge of de-identification, tokenization, audit trails, and API-based self-service data portals.
• Familiarity with international data transfer regulations (ICH E17, GDPR Article 46).

Technical & AI/ML Skills

AI/ML

• Experience developing and deploying ML models in regulated pharma environments.
• Hands-on experience with AI-powered portfolio optimization or predictive modeling.
• Strong understanding of MLOps, model validation, drift detection, explainability (SHAP, LIME), and AI governance.
• Familiarity with Databricks, MLflow, Kubeflow, SageMaker, Azure ML, TensorFlow, PyTorch, scikit-learn.
• Knowledge of federated learning and privacy-preserving AI.
• Understanding of the regulatory AI landscape (FDA guidance, EU AI Act)

Data & Engineering

• Strong foundation in Agile/Scrum, CI/CD, and iterative product delivery for data and AI products.
• Familiarity with GxP, 21 CFR Part 11, GDPR, and ICH E17.
• Knowledge of data standards (CDISC, OMOP, FAIR), metadata management, and lineage.
• Experience with cloud-native ecosystems (AWS, Snowflake, Databricks), API platforms, and AI deployment technologies (Docker, Kubernetes).
• Proficiency with product tools such as Jira, Confluence, and Miro, Better is out there. Better medications, better outcomes, better science. But progress doesn't happen without people - people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let's be those people.

• Discover endless opportunities to grow your talent and drive your career, whetherit'sthrough a promotion or lateral move, at home or internationally.
• Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.
• Takegood careof yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare,preventionand wellness programs and at least14 weeks' gender-neutral parental leave., Watch our ALL IN video (https://www.youtube.com/watch?v=SkpDBZ-CJKw&t=67s) and check out our Diversity Equity and Inclusion actions at sanofi.com (https://www.sanofi.com/en/our-responsibility/equality-and-inclusiveness) !

US and Puerto Rico Residents Only

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally inclusive and diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; natural or protective hairstyles; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

North America Applicants Only

The salary range for this position is

$187,500.00 - $270,833.33

All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs. Additional benefits information can be found through the LINK (https://benefits.sanofiusallwell.com/fleet/public/index/ba511bf8-5c32-4828-9861-ab985fffab90/?cid=sanofi) .

Global Terms & Conditions and Data Privacy Statement (https://www.sanofi.com/en/careers/global-terms-and-conditions/)

Sanofi is dedicated to supporting people through their health challenges. We are a global biopharmaceutical company focused on human health. We prevent illness with vaccines, provide innovative treatments to fight pain and ease suffering. We stand by the few who suffer from rare diseases and the millions with long-term chronic conditions.

Ready to push the limits of what's possible? Join Sanofi in one of our corporate functions and you can play a vital part in the performance of our entire business while helping to make an impact on millions around the world., Sanofi has embarked on an ambitious digital transformation, with data acceleration and the adoption of AI and machine learning at its core to enhance R&D, manufacturing, and commercial outcomes-ultimately delivering better medicines and vaccines to patients faster. Within this effort, the R&D Data & AI Products and Platforms team plays a pivotal role by building the data foundations and AI solutions needed to democratize R&D data and scale advanced analytics across the organization. As part of Sanofi's AI-first strategy, we are seeking a Product Line Owner to lead two high-impact domains: Project & Pipeline Analytics and Portfolio Management , enabling data-driven portfolio decisions, enhanced pipeline visibility, and optimized R&D investment through platforms such as Planisware, Enrich, and Veeva Vault RIM; and External Data Sharing Solutions , supporting secure, compliant, and scalable data exchange with partners using privacy-preserving AI, federated learning, and real-world evidence environments. This role will define the strategy, roadmap, and delivery of products that ensure harmonized, trusted, analytics-ready R&D data, working closely with scientific, regulatory, clinical, and digital teams to shape portfolio decisions, optimize pipeline investments, and expand Sanofi's external data ecosystem through innovative and secure data-sharing capabilities. About Sanofi We're an R&D-driven, AI-powered biopharma company committed to improving people's lives and delivering compelling growth. Our deep understanding of the immune system - and innovative pipeline - enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people's lives., With more than 100,000 people in 100 countries, Sanofi is transforming scientific innovation into healthcare solutions around the globe. Discover more about us visiting www.sanofi.com or via our movie We are Sanofi (https://youtu.be/96EwNjb1TLo) As an organization, we change the practice of medicine; reinvent the way we work; and enable people to be their best versions in career and life. We are constantly moving and growing, making sure our people grow with us. Our working environment helps us build a dynamic and inclusive workplace operating on trust and respect and allows employees to live the life they want to live. All in for Diversity, Equity and Inclusion at Sanofi - YouTube (http://www.youtube.com/watch?v=SkpDBZ-CJKw&t=2s)