Sr. Scientist, Delivery Sciences

Moderna Therapeutics
Cambridge, MA, United States
3 days ago

Role details

Contract type
Permanent contract
Employment type
Full-time (> 32 hours)
Experience level
Expert
Experience required
2 years minimum
Working hours
Regular working hours

Tech stack

Artificial Intelligence Data Analysis Data Analytics

Job description

Experteer Overview In this role you will lead development of targeted LNP formulations to enable extra-hepatic delivery and advance structure-function understanding through advanced analytics. You will scale high-throughput formulation and AI/ML-enabled workflows to accelerate discovery within a fast-moving, cross-functional R&D environment. You’ll guide experimental design, data interpretation, and collaboration across teams to meet program milestones. This position combines scientific leadership with hands-on formulation science to push delivery technologies beyond liver targeting. Compensation / Benefits * Lead targeted, extra-hepatic LNP delivery programs from hypothesis generation to in-vivo evaluation * Develop and optimize LNP self-assembly, composition, payload loading, and surface modifications for tissue/cell-type specificity * Leverage high-throughput formulation, automation, and AI/ML-enabled analysis to accelerate discovery and data-driven decisions * Independently design and execute experiments; communicate results to multidisciplinary teams and leadership * Apply advanced physicochemical/biophysical characterization (DLS, CryoEM, SAXS, ITC, NMR, nFCM) to elucidate structure-function relationships * Maintain rigorous electronic lab notebooks, SOPs, and documentation * Provide scientific leadership and mentorship, collaborating with cross-functional teams and external partners to meet project milestones Tasks * Ph.D. in a relevant discipline with 2+ years of experience * Deep expertise in LNP design, formulation, and physicochemical characterization; experience with targeted/extra-hepatic delivery preferred * Experience implementing high-throughput workflows, lab automation, and AI/ML-enabled data analysis * Proven leadership mentoring scientists and collaborating cross-functionally in a fast-paced environment * Proficiency with analytical techniques for nanoparticle size, morphology, composition, and stability assessment Key requirements * competitive healthcare * well-being resources (fitness, mindfulness, mental health) * family planning benefits * generous paid time off * sabbatical and global recharge days * equity or annual incentive potential

Requirements

and execute experiments; communicate results to multidisciplinary teams and leadership * Apply advanced physicochemical/biophysical characterization (DLS, CryoEM, SAXS, ITC, NMR, nFCM) to elucidate structure-function relationships * Maintain rigorous electronic lab notebooks, SOPs, and documentation * Provide scientific leadership and mentorship, collaborating with cross-functional teams and external partners to meet project milestones Tasks * Ph.D. in a relevant discipline with 2+ years of experience * Deep expertise in LNP design, formulation, and physicochemical characterization; experience with targeted/extra-hepatic delivery preferred * Experience implementing high-throughput workflows, lab automation, and AI/ML-enabled data analysis * Proven leadership mentoring scientists and collaborating cross-functionally in a fast-paced environment * Proficiency with analytical techniques for nanoparticle size, morphology, composition, and stability assessment Key requirements * competitive aaa

Benefits & conditions

aaaaaF_ * well-being resources (fitness, mindfulness, mental health) * family planning benefits * generous paid time off * sabbatical and global recharge days * equity or annual incentive potential

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