Senior Scientist, PBPK

duties and responsibilities are as follows:* As the Senior Scientist, PBPK, you will develop, verify, and apply PBBM and PBPK models using platforms such as Simcyp, GastroPlus, or equivalent software.* As the Senior Scientist, PBPK, you will support prediction and assessment of oral absorption, food effects, bioavailability, formulation bridging, dissolution, and particle size specifications, including virtual bioequivalence.* As the Senior Scientist, PBPK, you will perform model calibration, sensitivity analyses, scenario testing, and uncertainty assessments to inform project decisions.* As the Senior Scientist, PBPK, you will collaborate with laboratory scientists to design and interpret in vitro studies supporting model development and validation.* As the Senior Scientist, PBPK, you will support the development of clinically relevant dissolution methods and in vitro-in vivo links where appropriate.* As the Senior Scientist, PBPK, you will communicate modelling outcomes through technical

reports, project team presentations, regulatory documents, and scientific publications.* As the Senior Scientist, PBPK, you will contribute to advancing modelling methodologies, automation, and integration of AI/ML-enabled predictive tools. ROLE REQUIREMENTS To be successful in your application to this exciting role as the Senior Scientist, we are looking to identify the following on your profile and past history: * A Degree or higher level in Pharmaceutical Sciences, Biopharmaceutics, Pharmacokinetics, Pharmacometrics, Chemical Engineering, or a related scientific discipline.* Demonstrated expertise in PBPK, PBBM, pharmacometrics, mechanistic modelling, or model-informed drug development.* Strong understanding of oral absorption, dissolution, permeability, biopharmaceutics, and pharmacokinetics.* Experience with PBPK/PBBM modelling software such as Simcyp, GastroPlus, PK-Sim, or similar platforms.* Evidence of proven ability to apply modelling solutions to pharmaceutical development challenges.Key Words: Senior / Scientist / Biopharmaceutics / Modelling / Simulation / PBPK / PBBM / Pharmacokinetics / Regulatory / Drug Development / Modelling / Modeling / Drug Product / Mechanistic Modelling / Pharmacokinetics / Drug Discovery / Simcyp / GastroPlus / PK-Sim / Python / MATLAB / R Programming #J-18808-Ljbffr